Bioxydyn is an imaging CRO delivering high-quality data for imaging studies for the pharmaceutical industry, biotech and academic research.
Our advanced imaging biomarkers and rigorous study management generate deep insight into disease progression and drug response, supporting smarter development decisions and better patient outcomes.
Bioxydyn is an imaging CRO delivering high-quality data for imaging studies for the pharmaceutical industry, biotech and academic research.
Our advanced imaging biomarkers and rigorous study management generate deep insight into disease progression and drug response, supporting smarter development decisions and better patient outcomes.
Bioxydyn specialises in quantitative MRI biomarkers that provide safe and non-invasive insight into disease progression and drug response.
We generate robust pharmacodynamic measurements of tissue and organ function across a wide range of disease areas. Our validated biomarkers deliver repeatable, high-quality data, enabling rich, specific insights from smaller patient populations. With decades of experience and operational excellence, we deliver rigorous and efficient studies thanks to industry-leading expertise.
Read moreFrom study design to database lock, Bioxydyn offers one integrated solution.
We design endpoints, documentation & MR protocols aligned to your objectives.
We harmonise scanners, train site teams quickly and qualify your sites.
Sites upload data using our platform VoxelFlow. We monitor uploads and QC fast.
We run validated analysis pipelines with full auditability.
We deliver decision-ready outputs in your preferred data format. We archive documentation and data.
Bioxydyn offers imaging biomarkers for respiratory diseases such as cystic fibrosis, asthma, pulmonary hypertension, interstitial disease and COPD. We have extensive expertise in quantitative MRI methods for assessing regional lung function, including measurements of ventilation and perfusion.
Read moreBioxydyn provides advanced functional MRI biomarkers in oncology, using techniques such as diffusion MRI and dynamic contrast-enhanced (DCE) MRI, and is the leading CRO offering tumor hypoxia imaging to inform therapy effectiveness or characterise tumour physiology.
Read moreBioxydyn has delivered multiple studies for pharmaceutical companies using quantitative imaging of inflammation in a wide range of diseases, including functional imaging of joints in rheumatoid arthritis and osteoarthritis and renal imaging in nephritis.
Read moreBioxydyn is experienced in the deployment of quantitative MRI methods for neuroscience in conditions including multiple sclerosis, neurodevelopmental conditions, dementia and neuro-oncology. Our collaboration with Queen Square Analytics enables advanced AI methods for patient stratification with a focus on multiple sclerosis and Alzheimer's disease.
Read moreBioxydyn offers MRI measurement of liver transporter fluxes using dynamic contrast-enhanced MRI (DCE-MRI), plus other imaging biomarkers, including relaxation time measurements, in the investigation of liver diseases.
Read moreMost successful drug developments involve a careful balance between safety and efficacy. The FDA recognises the importance of biomarkers (including imaging biomarkers) in drug safety assessment. Imaging biomarkers of drug safety have played a major role in avoiding drug-induced harm to many important organ systems, including liver, lung, brain, heart, and the musculoskeletal system.
Bioxydyn trains and works with any imaging site defined by the customer following a simple electronic qualification process. Most globally installed MRI equipment can be set up to perform our quantitative methods, and Bioxydyn can provide quick and accurate instruction and assistance as required.
Whatever the study protocol, Bioxydyn can work with your preferred imaging sites, or suggest alternatives with known expertise in a specific imaging technique.
Founded in 2009, Bioxydyn has a strong track record in the delivery of imaging services in clinical trials.
Bioxydyn has delivered numerous studies for multiple pharma/biotech and clinical/academic clients. Bioxydyn also has a strong track record in supporting, winning and delivering grant funded studies.
